WebThis chemical has been used as a marker of exposure to flavoring vapors in investigations evaluating lung disease in microwave popcorn manufacturing facilities. 1 Acetoin (also … WebDiacetyl Exposure and Effects on Lung Function. Findings from studies of workers engaged in microwave popcorn and flavorings production were used by NIOSH to estimate worker risks for occupational lung disease by …
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Diacetyl is a chemical that was found to be a prominent volatile constituent in butter flavoring and air at the microwave popcorn plant initially investigated by NIOSH. Diacetyl is also known as the alpha-diketone, 2,3-butanedione, or by its Chemical Abstracts Service (CAS) number, 431-03-08. NIOSH has … See more Flavorings are often complex mixtures of natural and man-made substances. The U.S. Food and Drug Administration (FDA) evaluates flavoring ingredients to determine whether … See more The alpha-diketone, 2,3-pentanedione, has received attention as a flavoring substitute for diacetyl. It is also known as acetyl propionyl or by CAS number 600-14-6. It is structurally … See more As a group, these publications raise concerns that the toxicologic effects of diacetyl may be shared with close structural analogs used in food manufacturing such as 2,3-hexanedione and 2,3 … See more WebNov 1, 2024 · Bronchiolitis obliterans (BO) is a debilitating disease of the small airways that can develop following exposure to toxic chemicals as well as respiratory tract infections. BO development is strongly associated with diacetyl (DA) inhalation exposures at occupationally relevant concentrations or severe influenza A viral (IAV) infections. … how to change password in microsoft exchange
Clinical bronchiolitis obliterans in workers at a microwave …
WebThe National Institute for Occupational Safety and Health (NIOSH) objective in establishing recommended exposure limits (RELs) for diacetyl and 2,3-pentanedione is to reduce the risk of respiratory impairment (decreased lung function) and the severe irreversible lung disease obliterative bronchiolitis associated with occupational exposure. WebApr 12, 2024 · Yeah, so again, I think the new exposure stuff is really interesting. I mentioned briefly, the, again, popcorn lung, diacetyl exposure. But also what we're seeing is silica exposure and things like other exposures, which were old exposures. So things we saw of mining, of construction now in new industries. WebDiacetyl and 2,3-pentanedione inhalation have been suggested as causes of severe respiratory disease, including bronchiolitis obliterans, in food/flavoring manufacturing workers. Both compounds are present in many food items, tobacco, and other consumer products, but estimates of exposures associated with the use of these goods are scant. michael orenstein actor